Chapter 1: Conceptualization First some history: Kraepelin is the important grade in this chapter. Differentiated manic-depressive disease from frenzy praecox (SCZ). unify melancholia (DEP) and circular psychoses (BPAD, SAFD) into one category. His fundamental insight was that retort is mention. Bleueler woolly the distinction again, putting SCZ and BPAD on a spectrum. SCZ sx were key and affective sx were non-specific. He set the stage for the unipolar-bipolar distinction. unipolar vs. bipolar: G/J spend much time careen that unipolar-bipolar belief is less helpful than the idea of recurrence. Heterogeneity: Unipolar illness very heterogeneous group. So is bipolar. Early categorisation schemes (1) turn out different epidemiology between MD, Md, dM and dm groups. Rates: umteen studies show that unipolar:bipolar ~1:1. So what is the unipolar/bipolar distinction: Phenomenology of Depression| bipolar| Unipolar| inhering Course| | | Age of on set| Young| grey| | press range| Wider range| # sequences| more(prenominal)| little| Length guess| piteouser| Longer| Cycle length| Longer| shorter| Precipitant of case| more than important at onset| ?| Inter-episode mood lability| much| less(prenominal)| | | | Marital Status| Not a RF| RF| | | | Epedimiology| | | Life time risk| 1.
5%| 10-15%| Gender| M=F| F>M| SA| to a greater extent| little| | | | genetic science| More hereditary| little| | | | Biological| | | ache aesthesia| Less| More| Sleep duration| Long| bypass| Seasonal| D-fall/winter M-spring/summer| D-spring| | | | Pharm| | | Response t! o AD| Less| More| Speed of response to AD| More| Less| Tolerance to ADs| More freq| Less freq| Switch w/ ADs| More| Less| Prophylactic response to ADs| Less| More| roughly notes on mania: 1) unipolar mania is probably marvelous (<10% of BPAD). 2) Primacy of mania (2): all depression follows excitation take (mania, hypomania,...If you want to get a full essay, order it on our website: OrderCustomPaper.com
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